Provided is a medical article with improved moisture vapor transmission rate of the pressure sensitive adhesive layer with a miscible composition. The medical article has a backing, a pressure sensitive adhesive layer with acid-functional groups or basic-functional groups, an MVTR-modifying composition that is basic when the PSA comprises an acidic-functional group or is acidic when the PSA comprises a basic-functional group, and a filtration layer disposed between the MVTR-modifying layer and the PSA layer. The MVTR-modifying composition is miscible with the PSA, and contact between the MVTR-modifying composition and the PSA causes an acid-base reaction to form a poly-salt and increase moisture permeability of at least a portion of the PSA layer.
