A drug delivery system for use with a drug delivery device includes a support member, a compression member spaced from the support member to define a gap between the support member, and the support member and the compression member. A mechanical connection including a plurality of connecting members positioned and extending between the support member and the compression member, and an attachment connected to the compression member and configured to apply a rotational force to the compression member opposite the support member. Element. The mechanical connection is configured such that rotation of the compression member relative to the support member causes the compression member to be drawn toward the support member, reducing the gap therebetween.薬剤送達デバイスとともに使用するための薬剤送達システムは、支持部材と、支持部材との間に間隙を画成するように支持部材から隔置された圧縮部材と、支持部材と圧縮部材との間に位置し、支持部材と圧縮部材との間に延びる複数の連結部材を含む機械的連結と、圧縮部材に連結され、支持部材に相対する圧縮部材に対して回転力をかけるように構成された付勢要素とを含む。機械的連結は、支持部材に相対する圧縮部材の回転により圧縮部材が支持部材の方へ引き寄せられて、それらの間の間隙が低減するように構成される。