The invention discloses a gingko biloba compound oral liquid for preventing and/or treating cardiovascular and cerebrovascular diseases and a preparation method thereof. The preparation method of the gingko biloba compound oral liquid provided by the invention comprises the following steps: (1) preparing a water-soluble gingko leaf extract； (2) preparing a medlar extract； (3) preparing a gingko biloba compound oral liquid； (4) preparing the Gingko biloba compound oral liquid. The ginkgo biloba compound oral liquid provided by the invention can improve cardiovascular and cerebrovascular diseases, and the content of ginkgolic acid is 1 ppm or less. Ginkgo biloba compound oral liquid prepared according to the method of the present invention has significant effects on hypoxia, cardiovascular and cerebrovascular diseases, especially myocardial ischemia, prevention of myocardial infarction, and reduction of blood viscosity； ginkgo biloba extract and alfalfa extract. The combination of things is relatively scientific and reasonable, and the two have better complementary synergistic effects, and have obtained satisfactory clinical verification.
