Guillemont, Jerome Emile Georges,Heeres, Jan,Lewi, Paulus Joannes
申请号：
AU2005288866
公开号：
AU2005288866B2
申请日:
2005.09.29
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
HIV replication inhibitors of formula (I) a -oxide, a pharmaceutically acceptable addition salt, a quaternary amine or a stereochemically isomeric form thereof, wherein A is -CH-CH- , -CH=CH- , -C≡C- ； R is hydrogen, aryl, formyl, Calkylcarbonyl, Calkyl, Calkyloxycarbonyl, Rhydroxy, halo, Calkyl, carboxyl, cyano, -C(=O)R, nitro, amino, mono- or di(Calkyl)amino, polyhalomethyl； X is -NR-, -O-, -S-, -S(=O)； R is H, Calkyl, halo ； R is H, Calkyl, halo ； R is nitro, amino, mono- and diCalkylamino, aryl, halo, -CHO, -CO-R, -COOR, -NH-C(=O)H, -NH-C(=O)R, -CH=N-O-R； R is Calkyl, amino, mono- or di(Calkyl)amino or polyhaloCalkyl； R is hydrogen, Calkyl, arylCalkyl； R is hydrogen, Calkyl, aryl； p is 1 or 2； aryl is optionally substituted phenyl； pharmaceutical compositions containing these compounds as active ingredient and processes for preparing said compounds and compositions.
