University Of British Columbia;The Centre for Drug Research and Development
发明人:
Babcook, John Stephen,McNagny, Kelly Marshall,Roskelley, Calvin D.,Hedberg, Bradley John,Snyder, Kimberly Ashely,Hughes, Michael R.
申请号:
AU2014339719
公开号:
AU2014339719A1
申请日:
2014.10.21
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The present invention is directed to compositions of matter useful for the treatment of cancer in mammals and to methods of using those compositions of matter for the same. Antibodies specific for podocalyxin designated Ab1 and 3G2 are disclosed, as is the use of said antibodies for the inhibition of growth of a tumor that expresses podocalyxin, and the use of said antibodies for targeting tumour endothelial cells that express podocalyxin.