ANTIBODY CONSTANT REGION VARIANT

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专利权人:

Chugai Seiyaku Kabushiki Kaisha

发明人:

申请号：

EP11750823.4

公开号：

EP2543730B1

申请日:

2011.03.04

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

An antibody constant region having reduced binding activity with Fcγ receptor as a result of modification of the amino acid sequence of the constant region of an antibody was researched for the purpose of drug development. As a result, a novel constant region sequence having reduced binding activity with Fcγ receptor compared with a conventional antibody constant region was discovered.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/