An apparatus for unsheathing and resheathing a needle device. The apparatus has a housing, a cam member that is movable in an axial direction relative to the housing, a ratchet member that is rotatable relative to the housing and movable in the axial direction between a first position and a second position upon movement of the cam member, and a clamp having at least two jaw members, configured to receive at least a portion of a needle sheath. In the first position of the ratchet member, the jaw members are in an open configuration for receipt or release of the needle sheath, and in the second position of the ratchet member, the ratchet member and/or the cam member holds the jaw members in a gripping position for gripping the needle sheath.
