METHODS TO IDENTIFY A LYN KINASE ACTIVATOR, AND TO TREAT DIABETES IN A HUMAN, KIT, AND, COMPOSITION

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专利权人:

MELIOR PHARMACEUTICALS I; INC

发明人:

ANDREW REAUME,MICHAEL SAPORITO

申请号：

BRPI0807928

公开号：

BRPI0807928A2

申请日:

2008.02.20

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

The present invention relates to methods of identifying activators of lyn kinase by preincubating a test compound in the presence of lyn kinase； adding ATP and substrate to the lyn kinase and test compound； incubating the test compound, lyn kinase, ATP, and substrate； and measuring phosphorylation level of the substrate, whereby an increase in the phosphorylation of the substrate indicates that the test compound is an activator of lyn kinase.

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中国工程科技知识中心

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http://www.ckcest.cn/home/