Anand R. Baichwal,Troy W McCALL,Lirong LlU,Steve LABUDZINSKI
申请号:
US14195127
公开号:
US20140242166A1
申请日:
2014.03.03
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed are sustained release oral solid dosage forms comprising a therapeutically effective amount of a medicament having a solubility of more than about 10 g/l; a pH modifying agent; and a sustained release matrix comprising a gelling agent, said gelling agent comprising a heteropolysaccharide gum and a homopolysaccharide gum capable of cross-linking said heteropolysaccharide gum when exposed to an environmental fluid, said dosage form providing a sustained release of said medicament after oral administration to human patients.