Patent Specification: "composition comprising aflibercept, folinic acid, 5-fluorouacil (5-fu) and irinocetan (folfiri)". The present invention relates to a pharmaceutical composition comprising aflibercept, folinic acid, 5-fluorouracil (5-fu) and irinocetan (folfiri) useful in the treatment of colorectal cancer (crc).resumo patente de invenção: "composição compreendendo aflibercept, ácido folínico, 5-fluorouacila (5-fu) e irinocetano (folfiri)". a presente invenção refere-se à composição farmacêutica compreendendo aflibercept, ácido folínico, 5-fluorouracila (5-fu) e irinocetano (folfiri) úteis no tratamento de câncer colorretal (crc).