WEGMANN, FRANK,LANGEDIJK, JOHANNES PETRUS MARIA,CUSTERS, JEROME HUBERTINA HENRICUS VICTOR,BOCKSTAL, VIKI,KALLA, MARKUS
申请号:
CA3066573
公开号:
CA3066573A1
申请日:
2018.06.14
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Poxvirus vectors encoding a synthetic HIV envelope antigen and other HIV antigens, as well as compositions containing such poxvirus vectors and uses of such poxvirus vectors as vaccines to provide improved immunity against HIV, are provided. Also provided are vaccine combinations containing the disclosed poxvirus vectors, adenovirus vectors encoding one or more HIV antigens, and one or more isolated HIV antigenic polypeptides, and methods of using the vaccine combinations to provide improved immunity against HIV.