A medical device for controlling a release of bioactive agents to a body of patient. The medical device includes a support structure and a coating disposed at least partially covering the support structure. The coating includes a biodegradable outer and inner layer. First beads are disposed between the layers. A therapeutically effective amount of a first bioactive agent is disposed within pores of the first beads. Second beads are disposed between the support structure and the inner layer. A therapeutically effective amount of a second bioactive agent is disposed within the pores of the second beads. The first beads are releasable in response to at least partial biodegradation of the outer layer, and the second beads are releasable after the first beads in response to at least partial biodegradation of the inner layer. The coating may include a nonwoven matrix.
