Phenyl amino pyrimidine bicyclic compounds and uses thereof

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专利权人:

YM Biosciences Australia Pty Ltd

发明人:

Christopher John Burns

申请号：

US13830152

公开号：

US08809359B2

申请日:

2013.03.14

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention relates to phenyl amino pyrimidine bicyclic compounds formula I which are inhibitors of protein kinases including JAK kinases. In particular the compounds are active against JAK1, JAK2, JAK3 and TYK2 kinases. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants； hyperproliferative diseases including cancer and myeloproliferative diseases； viral diseases； metabolic diseases； and vascular diseases.

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