What is disclosed is certain derivatives of the benzoxazine keto-amide with chemical formula (I), or its pharmaceutically acceptable salt, (chemical formula (I)) its serve as mineralocorticoid (MR) receptor modulators that can be reduced oxidative stress in endothelium and therefore improve vascular function, it is related to the method with their potential therapeutical uses of what, be related to the pharmaceutical composition comprising them and is related to the method for preparing these compounds with what.披露的是具有化學式(I)的苯并噁嗪酮酰胺的某些衍生物，或其藥學上可接受的鹽，(化學式(I))其充當可減少內皮中氧化應激並且因此改善血管功能的鹽皮質激素(MR)受體調節劑，涉及用於它們潜在的治療用途的方法，涉及包含它們的藥物組合物並且涉及用於製備這些化合物的方法。
