Heterocyclic compounds of Formula (I) shown herein. Also disclosed are pharmaceutical compositions containing the heterocyclic compounds and methods of using the heterocyclic compounds to mobilize hematopoietic stem cells and endothelial progenitor cells into the peripheral circulation. Further provided are methods for treating tissue injury, cancer, inflammatory disease, and autoimmune disease with the heterocyclic compounds.本發明係關於式(I)之雜環化合物,另揭露包含該雜環化合物之醫藥組成物以及使用該雜環化合物驅使造血幹細胞(HSC)及內皮前驅細胞(EPC)進入周邊血液循環的方法。本發明更提供一種使用該雜環化合物治療組織損傷、癌症、發炎性疾病、或自體免疫性疾病的方法。