Provided is a novel bleomycin hydrolase production promotor. Provided is a bleomycin hydrolase production promotor, natural moisturizing factor production promotor, and dry skin remedy, comprising as an active ingredient thereof one or a plurality of ingredients selected from the group consisting of chestnut rose extract, angelica root extract, cork tree bark extract, lamium album extract, rosemary extract, benzenesulfonyl GABA and erythritol.