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METHOD FOR THE TARGETED KILLING OF CELLS BY NUCLEOTIDE MOLECULES THAT ARE DIRECTED TO mRNA BINDING, AND ALSO NUCLEOTIDE MOLECULES AND APPLICATION KIT FOR SUCH USE
专利权人:
发明人:
Mirko LUDWIG,Tobias POEHLMANN,Rolf GUENTHER,Juliane REICHE
申请号:
US14770877
公开号:
US20160145623A1
申请日:
2014.02.26
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Nucleotide molecules are used for the targeted killing of cells, which bind with a nucleotide sequence to a single region of the mRNA which, according to sequencing analyses, is statistically very rarely subject to a mutation and, thus, also in case of increased mutation rates in the whole genome, reliably kills the cell without further mRNA binding or other influence on the cell being necessary.
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