A micro sensing system for real-time sensing a neurotrophic factor included in a body fluid includes a body, a neurotrophic factor channel formed in the body to allow a fluid flow therein, and a biosensor formed at the body to sense the neurotrophic factor, wherein the body fluid is extracted in a living body through the neurotrophic factor channel, and wherein the biosensor is disposed on a path of the neurotrophic factor channel to directly contact a body fluid flowing through the neurotrophic factor channel and senses a concentration of a neurotrophic factor in the body fluid.
