Activation mechanism for a medicament delivery device comprising a housing 20 elongated along a generally longitudinal axis, a spring-biased drive member 30, a locking unit 70, movable from a locked position, preventing longitudinal movement of said drive member 30, to an unlocked position, a first activation member 60 movable relative to the housing 20 a second activation member 80 movable relative to the housing 20, and wherein the locking unit 70 comprises a key member 90, movable relative to the locking unit 70, wherein the first activation member 60 and the second activation member 80 are configured to move the locking unit 70 from the locked position to the unlocked position, wherein upon actuation, the first activation member 60 and the second activation member 80 cooperate in interacting with the key member 90 to move the key member 90 to the cooperating position and to move the locking unit70from the locked position to the unlocked position.