Ashantai J. Yungai,Burt Richards,Daniel A. Wettstein,Donald A. Mcleod,Kazuyuki Suzuki,Kraig M. Yager,Mark D. Shenderovich,Matthew Gregory Bursavich,Paul L. Bartel,Paul R. Sebahar,Robert J. Halter,Ryan
申请号：
BR112012008677
公开号：
BR112012008677A2
申请日:
2010.10.12
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
amino pyrimidine compounds with inhibitors of tbkl and / or ikk epsilon. The invention relates to certain amino pyrimidine compounds which inhibit tbk1 and / or ikk epsilon and which may therefore be applied in the treatment of inflammation, septic shock and / or primary open-angle glaucoma (poag).compostos amino-pirimidina com inibidores de tbkl e/ou ikk epsilon. a invenção diz respeito a certos compostos amino-pirimidina, que inibem tbkl e/ou ikk épsilon e os quais podem, portanto, ser aplicados no tratamento de inflamações, choque séptico e/ou glaucoma primário de ângulo aberto (poag).
