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LIQUID FORMULATION OF HIGHLY CONCENTRATED LONG-ACTING HUMAN GROWTH HORMONE CONJUGATE
专利权人:
HANMI SCIENCE CO.; LTD.
发明人:
Hyung Kyu LIM,Hyun Uk KIM,Sung Hee HONG,Sung Min BAE,Se Chang KWON
申请号:
US16045511
公开号:
US20180344866A1
申请日:
2018.07.25
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A liquid formulation of highly concentrated long-acting human growth hormone conjugate contains a pharmaceutically effective amount of the long-acting human growth hormone conjugate in which human growth hormone (hGH) is linked to an immunoglobulin Fc region, and an albumin-free stabilizer, said stabilizer comprising a buffer, a non-ionic surfactant, a sugar alcohol, and sodium chloride as an isotonic agent. A method for preparing the same is provided.
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