INDUCTION ANTI-TGF-SS DE FONCTION DE CELLULE OSSEUSE ET CROISSANCE OSSEUSE

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专利权人:

Vanderbilt University

发明人:

申请号：

EP16180079.2

公开号：

EP3141561A2

申请日:

2010.04.26

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The invention regards the modulation of TGF-β activity by administering to a subject an antibody that binds to TGF-β, thereby increasing bone growth, bone formation, bone mass and bone strength. The antibody acts to increase osteoblast number and function while at the same time decreasing osteoclast number and function. Such drugs are useful in the treatment of diseases or disorders such as osteoporosis, Paget's disease, metastatic bone cancer, myeloma bone disease, bone fractures, etc.

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中国工程科技知识中心

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