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INHIBITEUR DE DYSFONCTIONNEMENT D'ÎLOTS TRANSPLANTÉS DANS UN TRANSPLANT D'ÎLOTS
专利权人:
FUKUOKA UNIVERSITY;CHUGAI SEIYAKU KABUSHIKI KAISHA
发明人:
申请号:
EP06811729.0
公开号:
EP1941907B1
申请日:
2006.10.13
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present inventors investigated anti-IL-6 receptor antibodies for their effect in suppressing damage to transplanted islets after islet transplantation. As a result, they found that anti-IL-6 receptor antibodies reduced damage to transplanted islets, improved islet survival, and corrected hyperglycemia in recipients. Further, they revealed that administration of the anti-IL-6 receptor antibodies of the present invention suppressed the production of inflammatory cytokines by infiltrating cells after transplantation. Specifically, the present inventors discovered for the first time that damage to transplanted islets after islet transplantation can be suppressed by using anti-IL-6 receptor antibodies according to the present invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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