The invention relates to specific antibody drug conjugates (ADCs) of kinesin spindel protein inhibitors, active metabolites of said ADCs, methods for producing said ADCs, the use of said ADCs for the treatment and/or prevention of diseases and the use of said ADCs for the production of medicaments for the treatment and/or prevention of diseases, in particular hyperproliferative and/or angiogenic diseases such as, for example, cancer diseases.