A computer-implemented method for analyzing biophysiological periodic data includes receiving a stream of feature data points, determining whether each of the feature data points lies within or outside a predetermined limit, and eliminating a first subset of the feature data points in response to having determined that the each of the data points in the first subset lies outside the predetermined limit. The method further includes extracting a feature from the feature data points that lie within the predetermined limit over a time window, performing multiple hypothesis tests to determine whether or not the feature corresponds to a any of multiple hypothesis distributions, and qualifying the feature as a qualified estimate of an actual feature if the feature corresponds to statistical mean of a plurality of recent qualified estimates.