Modified release of 4 - methyl - 3 - [[4 - (3-pyridinyl) - 2 - pirimidinil] - amino] - N - [5 - (4 - methyl - 1H imidazol-1-yl) - 3 - (trifluoro methyl) phenyl] - benzamide Solubilized using organic acids

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专利权人:

NOVARTIS AG

发明人:

LI SHOUFENG,KUMAR SARAN,KAVIMANDAN NIKHIL JAVANT,LU ENXIAN

申请号：

CO13268350

公开号：

CO6801777A2

申请日:

2013.11.14

申请国别(地区):

CO

年份:

2013

代理人:

摘要：

Soluble pharmaceutical compositions of nilotinib or a pharmaceutically acceptable salt thereof were invented using one or more organic acids that function as a solubilizing agent, increasing the bioavailability of nilotinib and supressing the food effect associated with certain compositions of nilotinib. The pharmaceutical compositions are in the form of solid oral dosage forms, including capsules and tablets.

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中国工程科技知识中心

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