A physiological detection module and wearable electronic apparatus includes a bracelet, a display unit, an optical sensing unit, an electrode unit and a microneedle sensing unit. The bracelet includes a housing and two girdles. A circuit board of a physiological detection module is arranged inside the housing. The display unit is arranged on a front side of the housing and electrically connected to the circuit board. The optical sensing unit is arranged on a reverse side of the housing and electrically connected to the circuit board. The electrode unit is arranged on the bracelet and electrically connected to the circuit board. The microneedle sensing unit is arranged on the bracelet and electrically connected to the circuit board. Moreover, the optical sensing unit, the microneedle sensing unit and the electrode unit measure a physiological signal, and the display unit displays the physiological signal after the circuit board operates the physiological signal.一種生理檢測模組及穿戴式電子裝置,包括﹕一手環、一顯示單元、一光學式感測單元、一電極單元、一微針感測單元。該手環包含有一殼體及二環帶,該殼體其內部具有一生理檢測模組的電路板。該顯示單元設於該殼體的正面,並與該電路板電性連結。該光學式感測單元係設於該殼體的背面,並與該電路板電性連結。該電極單元係設於該手環上,並與該電路板電性連結。該微針感測單元設於該手環上,並與該電路板電性連結。其中,以該光學式感測單元、該微針感測單元、該電極單元以量測該生理訊號,並將該生理訊號經該電路板運算後以顯示於顯示單元上。