A device for connecting first and second medical fluid flow systems includes a linear movement carriage system that is positioned within a housing. The carriage system includes first (18a) and second connector holders (18b) configured to hold first (22a) and second connectors (22b) of the first and second medical fluid flow systems, respectively. A coupler holder (28) is configured to hold a coupler (32) and is positioned substantially between the first and second connector holders. The first (18a) and second connector holders (18b) and the coupler holder (28) are relatively moveable between a separated configuration, where the first (22a) and second connectors (22b) and the coupler (32) are located in relatively spaced apart positions, and a joined configuration, where the first (22a) and second connectors (22b) engage the coupler (32). An ultraviolet light source (62) is positioned in the housing so as to irradiate the first (22a) and second connectors (22b) and the coupler (32). A drive system transitions the first (18a) and second connector holders (18b) and the coupler holder (28) between the separated and the joined configurations.
