The present invention provides a preparation comprising fibrinogen and a sulfated polysaccharide as a one component composition or as a kit of parts comprising fibrinogen and sulfated polysaccharide as separated components.The present invention further provides a fibrin clot like structure obtainable by a defined process, a hemostatic patch, a two-component syringe system and various uses of the described preparations, fibrin clot like structures and patches.本發明提供一種包含血纖維蛋白元與硫酸化多醣之製劑,其呈單組分組成物形式或呈包含血纖維蛋白元及硫酸化多醣作為獨立組分之分裝部分之套組形式。本發明進一步提供一種可由所定義之方法獲得之血纖維蛋白凝塊樣結構、止血貼片、雙組分注射器系統,以及所述製劑、血纖維蛋白凝塊樣結構及貼片之各種用途。