NARAIN, Niven Rajin,McCOOK, John Patrick,JIMENEZ, Joaquin J.
申请号：
AU2019222786
公开号：
AU2019222786A1
申请日:
2019.08.26
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
#$%^&*AU2019222786A120190912.pdf#####PREVENTING OR MITIGATING CHEMOTHERAPY INDUCED ALOPECIA USING VITAMIN D 5 Abstract The invention provides methods and pharmaceutical compositions for preventing or mitigating chemotherapy-induced alopecia (CIA). The pharmaceutical compositions of the invention comprise an effective amount of a vitamin D compound in a topical 10 formulation. The invention has broad applications in chemotherapies that induce alopecia, for example taxane based chemotherapy for cervical cancer, endometrial cancer, ovarian cancer, fallopian tube cancer, primary peritoneal carcinoma, soft tissue sarcoma, or bone sarcoma. The pharmaceutical compositions of the invention can be advantageously administered before and/or concurrent with the chemotherapy. 15
