MENG, Dongfang,LI, Hong,YANG, Meng,RUIZ, Manuel de Lera,DEWNANI, Sunita, V.,JIAN, Tianying,PARKER, Dann, L., Jr.,ZHANG, Ting,CAMPEAU, Louis-Charles,HARPER, Bart,WOOD, Harold, B.,XU, Jiayi,BERGER, Rich
申请号:
EP16752841
公开号:
EP3258929A4
申请日:
2016.02.12
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present invention provides a compound of Formula I and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing unstable angina, refractory angina, myocardial infarction, transient ischemic attacks, atrial fibrillation, thrombotic stroke, embolic stroke, deep vein thrombosis, disseminated intravascular coagulation, ocular build up of fibrin, and reocclusion or restenosis of recanalized vessels. The compounds are selective Factor IXa inhibitors.