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Methods and pharmaceutical compositions for the treatment of cancer
专利权人:
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE);UNIVERSITÉ PARIS DIDEROT—;PARIS 7;ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP)
发明人:
Jean-Luc Poyet,Heriberto Bruzzoni-Giovanelli,Léonard Jagot-Lacoussiere
申请号:
US15119274
公开号:
US10358469B2
申请日:
2015.02.17
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to methods and pharmaceutical compositions for the treatment of cancer. In particular, the present invention relates to a polypeptide comprising or consisting of i) an amino acid sequence ranging from the phenylalanine residue at position 380 to the leucine residue at position 384 in SEQ ID NO: 1 or, ii) an amino acid sequence having at least 70% of identity with the amino acid sequence ranging from the phenylalanine residue at position 380 to the leucine residue at position 384 in SEQ ID NO: 1, or iii) an amino acid sequence which is a retro-inverso of the amino acid sequence ranging from the phenylalanine residue at position 380 to the leucine residue at position 384 in SEQ ID NO: 1 or, iv) an amino acid sequence which is retro-inverso of the amino acid sequence having at least 70% of identity with the amino acid sequence ranging from the phenylalanine residue at position 380 to the leucine residue at position 384 in SEQ ID NO: 1.
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