The present disclosure discloses a boron neutron capture therapy system comprising: a boron neutron capture therapy device and an α-amino acid-like boron trifluoride compound having a structure shown as formula (I) below:Wherein: R is selected from hydrogen, methyl, isopropyl, 1-methylpropyl, 2-methylpropyl, hydroxymethyl, 1-hydroxyethyl, benzyl or hydroxybenzyl； M is H or metal atom. The energy generated from the action of the neutron beam generated by the boron neutron capture therapy device on the α-amino acid-like boron trifluoride compound destroys tumor cell DNA. In another aspect, the present disclosure discloses a use of an α-amino acid-like boron trifluoride compound in the preparation of a medicament for tumor therapy.
