GERMAIN MATTHIEU,MEYRE MARIE EDITH,POTTIER AGNÈS,LEVY LAURENT
申请号：
IN201717021521
公开号：
IN201717021521A
申请日:
2017.06.20
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The present invention relates to a pharmaceutical composition comprising the combination of (i) at least one biocompatible nanoparticle and of (ii) at least one carrier comprising at least one pharmaceutical compound to be administered to a subject in need of such a pharmaceutical compound wherein the combination of the at least one biocompatible nanoparticle and of the at least one carrier comprising the pharmaceutical compound(s) potentiates the compound(s)of interest efficiency. The longest dimension of the biocompatible nanoparticle is typically between about 4 and about 500 nm and its absolute surface charge value is of at least 10 mV(10 m V). The carrier is in addition devoid of any surface sterically stabilizing agent. The invention also relates to such a composition for use for administering the pharmaceutical compound(s) in a subject in need thereof wherein the at least one biocompatible nanoparticle and the at least one carrier comprising the at least one pharmaceutical compound are to be administered separately in a subject in need of said pharmaceutical compound typically between more than 5 minutes and about 72 hours one from each other.
