MOSELEY, SCOTT EDWARD,DENKER, ANDREW E.,PAN, WEI-JIAN
申请号：
CA3057502
公开号：
CA3057502A1
申请日:
2018.03.29
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The disclosure features methods for treating hypophosphatasia (HPP) in a patient (e.g., an adult having HPP, such as an adult having pediatric-onset HPP, or an adolescent having HPP) exhibiting decreased pyrophosphate (PPi) or pyridoxal 5'-phosphate (PLP) concentrations in, e.g., a plasma sample, physical impairments, or decreased walking ability by administering a soluble alkaline phosphatase (sALP) to the patient.
