Kayvan NIAZI,Raymond WONG,Peter SIELING,Philip T. LIU
申请号：
US16536962
公开号：
US20200101149A1
申请日:
2019.08.09
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Two-component vaccine formulations and methods are contemplated where the vaccine has an adjuvant component and a therapeutic component. The therapeutic component comprises preferably a recombinant therapeutic virus encoding a therapeutic antigen while the adjuvant component comprises a non-host cell or immune stimulating portion thereof. Notably, use of the adjuvant component will result in significant uptake of the therapeutic component into immune competent cells, even in the absence of receptors for entry of the therapeutic component. In addition, such adjuvant also stimulates expression of the therapeutic antigen.
