A radial artery compression band is disclosed for circumferential placement around the wrist of a patient to apply hemostasis pressure to a wound, which includes a first arcuate band portion including a radially outwardly extending support frame, a second elongated band portion including a plurality of longitudinally spaced apart radially outwardly extending ramped engagement teeth, a third elongated band portion extending between the first and second band portions and including a radially inwardly facing compression structure for applying hemostasis pressure to the wound, and a band adjustment mechanism mounted within the support frame of the first arcuate band portion and including an axially rotatable shaft having a worm gear section with a continuous helical thread for selectively intermeshing with the ramped engagement teeth on the second elongated band portion to adjust band tension through axial rotation of the shaft.
