5- (biphenyl-4-yl) -3-phenyl-1,2,4-oxadiazolyl derivatives as binders at sphingosine 1-phosphate (sip) receptors

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专利权人:

Merck Serono S.A.

发明人:

Agnès Bombrun,Anna Quattropani,Charles Baker-Glenn,Chris Knight,Jérôme Dorbais,Jérôme Gonzalez

申请号：

BR112013000041

公开号：

BR112013000041A2

申请日:

2011.07.06

申请国别(地区):

BR

年份:

2019

代理人:

摘要：

5- (biphenyl-4-yl) -3-phenyl-1,2,4-oxadiazolyl derivatives as binders at the sphingosine 1-phosphate (sip) receptors. The present invention relates to compounds of formula (I) as selective s1 p1 inhibitors, as well as their use to treat multiple sclerosis and other diseases.derivados de 5-(bifenil-4-il) -3-fenil-1,2,4-oxadiazolila como ligantes nos receptores de 1-fosfato de esfingosina (sip). a presente invenção refere-se a compostos de fórmula (i) como inibidores de s1 p1 seletivos, bem como seu uso para tratar esclerose múltipla e outras doenças.

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中国工程科技知识中心

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