A surgical stapling instrument includes a tool assembly configured to eject staples. The tool assembly has a cartridge assembly and an anvil assembly movable relative to each other. The cartridge assembly and the anvil assembly are configured to move between open and closed positions. The surgical stapling instrument further includes at least one transducer disposed in at least one of the cartridge assembly and the anvil assembly. The transducers are adapted to effect vibrations to enhance stapling. In one embodiment, wires connect the transducers to a power generator. The power generator supplies energy to the transducers.