Refers to - substituted pyridyl carboxylic acid - cicloalquil of formula (i), where R1 is Halogen, c1-c4 alkyl - or or - (c1-c4 alkyl, optionally substituted the last 2 R2 is H, halogen,Among others R3 is C3 C6 cycloalkyl optionally substituted and R4A r4b are h, halogen, among others R5 is substituted Pyridine X is C2H4 - CH2 -, - and -Among others, and is or nr8 R8 is H or c1-c4 alkyl.It is a compound selected: acid (R \/ S) {3 - [3 - (ciclopentil {4 - [5 - (trifluoromethyl) pyridin-3-yl]} - acetyl phenyl) - amino] - 2-methylphenyl} propanoic acid among others.It also relates to a Pharmaceutical composition that comprises.These compounds are useful in the treatment of diseases associated with Pain (acute and chronic), inflammation induced Pain, Pelvic Pain, Pain associated with CancerPain associated with endometriosis and adenomyosis and endometriosis and cancer as such as such as endometriosis and proliferative DiseasesSe refiere a acidos piridil-cicloalquil-carboxilico sustituidos de formula (I), donde: R1 es halogeno, C1-C4-alquilo o O-(C1-C4-alquilo), los 2 ultimos opcionalmente sustituidos R2 es H, halogeno, entre otros R3 es C3-C6-cicloalquilo opcionalmente sustituido R4a y R4b son H, halogeno, entre otros R5 es piridina sustituida X es -C2H4-, CH2-Y-, entre otros Y es O o NR8 R8 es H o alquilo C1-C4. Es un compuesto seleccionado: acido (R/S) 3-{3-[(ciclopentil{4-[5-(trifluormetil)piridin-3-il]fenil}-acetil)-amino]-2-metilfenil}propanoico entre otros. Tambien se refiere a una composicion farmaceutica que la comprende. Dichos compuestos son utiles en el tratamiento de enfermedades asociadas con dolor (agudo y cronico), dolor inducido por inflamacion, dolor pelvico, dolor asociado con cancer, dolor asociado con endometriosis asi corno tambien endometriosis y adenomiosis como tales, cancer como tal, y enfermedades proliferativas como endometriosis
