KOSUDA, Kathryn M.,STINSON, Jordan A.,BOOPATHY, Archana V.,DIRCKX, Matthew,KLUGE, Jonathan A.,ZHANG, Yichen,PALMER, Carter R.,SCHRADER, Michael A.
申请号：
AU2019247655
公开号：
AU2019247655A1
申请日:
2019.04.02
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
Microneedle and microneedle devices including implantable silk-based tips for sustained dermal delivery of a vaccine, kits, as well as methods of manufacturing and using the same are described herein. In other embodiments, compositions and methods for controlled- or sustained- administration of a vaccine (e.g., an influenza vaccine) to provide improved immunogenicity and/or broad- spectrum immunity to a subject are also described.
