PROBLEM TO BE SOLVED: To provide a novel promoter for MHC molecule expression on a tumor cell surface.SOLUTION: A promoter for MHC molecule expression on a tumor cell surface includes a combination of (A) interferon γ (IFNγ) and (B) at least one selected from between pyrrolidones represented by general formula (1) (wherein R1 is a hydrogen atom or a 1-12C alkyl group) and sulfoxides represented by general formula (2) (wherein R2 and R3 are each a 1-12C alkyl group).COPYRIGHT: (C)2014,JPO&INPIT【課題】新たな腫瘍細胞表面MHC分子発現促進剤の提供。【解決手段】(A)インターフェロン・ガンマ(IFNγ)と、(B)下記一般式(1)で表されるピロリドン類及び下記一般式(2)で表されるスルホキシド類から選ばれる1種以上とを組み合わせてなる腫瘍細胞表面MHC分子発現促進剤。(式中、R1は、水素原子または炭素数1~12のアルキル基を示す。)(式中、R2及びR3は、それぞれ炭素数1~12のアルキル基を示す。)【選択図】なし
