Drug solution having reduced dissolved oxygen content, method of producing the same and drug solution containing unit having reduced dissolved oxygen content
It is intended to provide a drug solution which has a reduced dissolved oxygencontent and therefore suffers from little degradation caused by oxidation andhas a high stability with the passage of time; a method of producing the same; anda drug solution containing unit wherein a drug solution can be stored while maintaininga low dissolved oxygen content and therefore suffers from little degradationcaused by oxidation and has a high stability with the passage of time. A drug solutionhaving a reduced dissolved oxygen content for achieving the object as describedabove can be obtained by containing a drug solution in a drug solution container(15) made of a plastic material, which has an oxygen permeability at 25Cand 60%RH of 200 cm/m 24 h atm or more within 12 hours aftersteam sterilization or hot water sterilization and an oxygen permeability at25C and 60%RH of 100 cm/m 24 h atm or less in asteady state of oxygen permeability, sealing the container, then subjectingit to steam sterilization or hot water sterilization, storing it in an environmentprovided with a deoxidation means and, when the oxygen permeability of the above-describedplastic material attains the steady state, regulating the dissolved oxygenconcentration of the drug solution to 2 ppm or less.