The present Invention relates to a combination of Monoclonal Antibodies directed against CD38 and cytarabine, in which the Antibody is a Humanized Antibody that includes one or more of the complementarity determining regions that have a sequence of amino acids, or at least At least a heavy chain and a light chain.Farmaceutska kompozicija koja sadrži antitelo koje specifično prepoznaje CD38 i melfalan .