SULFONAMIDES BENZÉNIQUES AZA-ARYL1H-PYRAZOL-1-YL COMME ANTAGONISTS DE CCR(9)

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专利权人:

Inc.;ChemoCentryx

发明人:

申请号：

EP17184205.7

公开号：

EP3263564A1

申请日:

2013.02.28

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Compounds of formula (II) are provided that act as potent antagonists of the CCR(9) receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR(9). The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR(9)-mediated diseases, and as controls in assays for the identification of CCR(9) antagonists.

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