Humanised antibodies to toll-like receptor 2 and uses thereof

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专利权人:

OPSONA THERAPEUTICS LIMITED

发明人:

DELLACASAGRANDE JEROME

申请号：

NZ59744710

公开号：

NZ597447A

申请日:

2010.07.06

申请国别(地区):

NZ

年份:

2013

代理人:

摘要：

Patent No. 597447 Disclosed is a neutralising antibody, or an antigen binding portion thereof, comprising a light chain variable domain comprising the amino acid sequence DIVLTQSPATLSLSPGERATLSCRASESVEYYGTSLMQWYQQKPGQPPKLLIFGASNVES GVPDRFSGSGSGTDFTLKISRVEAEDVGMYFCQQSRKLPWTFGGGTKVEIK and a heavy chain variable domain comprising an amino acid sequence QVQLVQSGSELKKPGASVKLSCKASGFTFTTYGINWVRQAPGQGLEWIGWIYPRDGSTNF NENFKDRATITVDTSASTAYMELSSLRSEDTAVYFCARLTGGTFLDYWGQGTTVTVSS, wherein the antibody specifically binds to Toll-like Receptor 2.

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来源网址：

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