Pavel Pisa;Christoph Leder;Maxim Pavlenko;Alan D. King
发明人:
Christoph Leder,Alan D. King,Maxim Pavlenko,Pavel Pisa
申请号:
US11922633
公开号:
US08293701B2
申请日:
2006.06.21
申请国别(地区):
US
年份:
2012
代理人:
摘要:
An object of the invention is to provide methods and compositions relating to a vaccine against prostate cancer which includes a non-human-primate PSA for administration to humans to provide an immune response against human PSA. More generally, an object of the invention is to provide methods and compositions relating to using a non-human primate xenogeneic antigen (e.g. protein) in a human, wherein, with respect to the non-human primate xenogeneic antigen that is used, there are relatively few interspecies differences between the non-human primate xenogeneic antigen and the human self antigen in order to induce an optimal immune response in the human to its native self antigen.