A killed bacteria of one or more pathogenic bacterial species or an extract paredcelular, an extract of cell membrane, an extract of whole cell, or an isolated antigen thereof, parasu use in the treatment of a cancer in a specific organ or tissue in a subject, wherein the preparation, elextracto cell wall extract cell membrane extract whole cell or antigen aisladosuscita an immune response in the subject and wherein the pathogenic bacterial species is pathogenic in órganoo tissue corresponding specific to a healthy subject in the that: the cancer is found in the kidney and one or more pathogenic bacterial species are selected from Escherichia coli, Proteus mirabilis, Proteus vulgatus, Providentia species, Morganella species and Enterococcus faecalis or the cancer is found in the lung and one or more pathogenic bacterial species are selected deStreptococcus pneumoniae, Moraxella catarrhalis, Mycoplasma pneumoniae, Klebsiella pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Chlamydia pneumoniae and Legionella pneumophila oel cancer is located in the bone and the pathogenic bacterial species is Staphylococcus aureus oel cancer is located in the colon and one or more pathogenic bacterial species are selected from Bacteroides fragilis, Bacteroides vulgatus, Bacteroides thetaiotaomicron, Clostridium perfringens, Clostridium difficile, Escherichia coli, Salmonella enteritidis, Shigella flexneri and Yersinia enterocolitica or cancer is located in the prostate and one or more pathogenic bacterial species ofEscherichia coli, Corynebacterium species, Enterococcus faecalis and Neisseria gonorrhoeae are selected oel cancer is found in the skin and one or more pathogenic bacterial species deStaphylococcus aureus, Corynebacterium diphtheriae, Corynebacterium ulcerans and Pseudomonas aeruginosa are selected or cancer is located in the mouth and one or more pathogenic bacterial species are selected from Prevotellamelaninogenicus, anaerobic streptococci, viridans streptococ
