Systems (100) and methods (300) for controlling coughing by subjects (106) control the opening and closing of a valve (12) (as well as partially opening and/or partially closing) to establish and disestablish a fluid communication between the airway of the subject and atmospheric pressure. The valve is opened and closed more than once during individual exhalations by the subject. Control of the valve is adjusted based on a pressure level in or near the airway of the subject.
