KNU-INDUSTRY COOPERATION FOUNDATION;SUPADELIXIR INC.
发明人:
Jang-Hee HAHN,Dong-Young LIM
申请号:
US15664277
公开号:
US20170334965A1
申请日:
2017.07.31
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Provided is a peptide fragment derived from secreted frizzled protein 5 (Sfrp5), i.e., a peptide fragment selected from the group consisting of the peptides as set forth in SEQ ID NOs: 1 to 9 and a cosmetic composition for skin-whitening and/or inhibiting skin pigmentation comprising the same as an active ingredient. The peptide fragment inhibits melanin formation in melanocytes, thereby having an inhibitory activity against skin pigmentation. Further provided is a reagent for researching or analyzing the inhibition of Wnt signaling pathways comprising the peptide fragment.